ONE THING Peptide Retinal Cream: Dermatocare review
ONE THING / Peptide Retinal Cream is formulated with neurotransmitter-inhibiting (Botox-like) peptides, Signal peptides, and Copper Tripeptide-1. Note: This formulation does not contain growth-factor mimic peptides.
Overview
Skin type Dry, Combination/Normal
Skin concern Fine lines/Wrinkles
Key Ingredients Peptides, Retinal/Retinaldehyde, Niacinamide, Sodium Ascorbyl Phosphate, Hyaluronic acid
Specs Fragrance Free, Has silicone, Premium
Life stage
Formula highlight
- Signal peptide - Palmitoyl Tripeptide-5, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Pentapeptide-4
- Neurotransmitter-inhibiting (Botox-like) - Acetyl Hexapeptide-8
- Carrier peptide - Copper Tripeptide-1
- Barrier repair: Niacinamide (conc not found)
- Antioxidant: Sodium Ascorbyl Phosphate (conc not found)
- Contains Retinal (a retinoid) — sits at position 44 of 52 in the INCI, a trace/late-list co-active rather than the formula's lead position despite the product name.
- Hydrating - Hyaluronic Acid, Hydrolyzed Hyaluronic Acid, Sodium Hyaluronate
Keep in mind
- Does not contain an enzyme-inhibiting peptide.
- Ingredients under review is blank across the full INCI.
People also ask
This product complies with all applicable cosmetic safety regulations. Evaluations provided are based on Dermatocare's independent database criteria, which apply stricter benchmarks than standard regulatory guidelines.
Sensitive skin Cautious use: Contains ingredients flagged in our database as common contact sensitizers. Performing a 24-hour patch test is recommended prior to use.
Pregnancy: Consult Doctor - Contains Retinal, which is flagged on our Pregnancy Ingredient Database. Please consult your physician before using this product.
Teens Caution: Teens do not need peptides. Their primary purpose is anti-aging, which is unnecessary for young skin that naturally maintains robust collagen. Refer to our Teen Skincare Guide for full details.
No. It does not contain any ingredients currently flagged under Dermatocare's internal evaluation criteria. Refer to our Ingredients Under Review Guide for full database benchmarks.
No. It does not contain ingredients currently flagged for environmental persistence, bioaccumulation, or aquatic toxicity under Dermatocare's database criteria. Refer to our Environmental Screening Guide for full evaluation benchmarks.
Ingredient list
Water, Hydrogenated Polydecene, Glycerin, Dipropylene Glycol, Cetearyl Alcohol, Propanediol, Caprylic/Capric Triglyceride, 1,2-Hexanediol, Butyrospermum Parkii (Shea) Butter, Niacinamide, Vinyl Dimethicone, Hydrogenated Polyisobutene, Palmitic Acid, Limnanthes Alba (Meadowfoam) Seed Oil, Stearic Acid, Butylene Glycol, Synthetic Beeswax, Polyglyceryl-2 Stearate, Cetearyl Glucoside, Glyceryl Stearate, Polyacrylate-13, Stearyl Alcohol, Carbomer, Tromethamine, Ethylhexylglycerin, Xanthan Gum, Dextrin, Gardenia Florida Fruit Extract, Adenosine, Polyglyceryl-10 Laurate, Ethylhexyl Palmitate, Disodium EDTA, Sorbitan Isostearate, Macadamia Ternifolia Seed Oil, Phosphatidylcholine, Hyaluronic Acid, Hydrolyzed Hyaluronic Acid, Sodium Hyaluronate, Cholesterol, Phytosteryl/Behenyl/Octyldodecyl Lauroyl Glutamate, Aluminum/Magnesium Hydroxide Stearate, Brassica Campestris (Rapeseed) Sterols, Hydrogenated Lecithin, Polyglyceryl-10 Oleate, Retinal, Sodium Lactate, Palmitoyl Tripeptide-5, Polysorbate 20, Potassium Cetyl Phosphate, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Caprylyl Glycol, Sodium Ascorbyl Phosphate, Palmitoyl Tripeptide-1, Acetyl Hexapeptide-8, Palmitoyl Tetrapeptide-7, Copper Tripeptide-1, Palmitoyl Pentapeptide-4 (cross verified at https://www.nykaa.com/one-thing-peptide-retinal-cream/p/21017995?skuId=21017977).
Source: https://incidecoder.com/products/one-thing-peptide-retinal-cream
Date: 15 September 2026
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