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NIOD Copper Amino Isolate Serum 3 1:1 (CAIS3)

NIOD Copper Amino Isolate Serum 3 1:1 (CAIS3): Dermatocare review

NIOD / Copper Amino Isolate Serum 3 1:1 (CAIS3) is formulated with Signal peptides, Copper Tripeptide-1, and enzyme-inhibiting peptides. Note: This formulation does not contain neurotransmitter-inhibiting (Botox-like) peptides or growth-factor mimic peptides.

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Automated INCI screening built on database benchmarks architected by Dr. Surbhi, MD (Dermatologist).

Last updated 15 September 2026 · How we evaluate?

Disclaimer

Overview

Skin type Oily, Combination/Normal, Dry

Skin concern Fine lines/Wrinkles, Rosacea/Sensitive skin

Key Ingredients Peptides, Hyaluronic acid

Specs Fragrance Free, Silicone free, Premium

Life stage

TeensCaution
PregnancyCompatible

Formula highlight

  • Carrier peptide - Tripeptide-1 Copper Acetate 1%
  • Signal peptide - Tripeptide-29, Tripeptide-1 Acetate 1%, Tripeptide-2, Acetyl Tetrapeptide-2
  • Enzyme-inhibiting peptide - Myristoyl Nonapeptide-3
  • Hydrating - Sodium Hyaluronate Crosspolymer, Glycogen

Keep in mind

  • Does not contain a neurotransmitter-inhibiting (Botox-like) peptide.
  • Ingredients under review is blank across the full INCI.

People also ask

This product complies with all applicable cosmetic safety regulations. Evaluations provided are based on Dermatocare's independent database criteria, which apply stricter benchmarks than standard regulatory guidelines.

Sensitive skin Cautious use: Contains ingredients flagged in our database as common contact sensitizers. Performing a 24-hour patch test is recommended prior to use.

Ingredient list

Aqua/Water/Eau, Glycerin, Tripeptide-29, Tripeptide-1 Copper Acetate, Tripeptide-1 Acetate, Myristoyl Nonapeptide-3, Tripeptide-2, Acetyl Tetrapeptide-2, Sodium Hyaluronate Crosspolymer, Glycogen, Propanediol, Pentylene Glycol, Dimethyl Isosorbide, Ethoxydiglycol, Isoceteth-20, Leuconostoc/Radish Root Ferment Filtrate, Caprylyl Glycol, Ethylhexylglycerin, Phenoxyethanol, Chlorphenesin.

Source: https://niod.com/en-us/copper-amino-isolate-serum-3-11-cais3-serum-100368.html
Date: 15 September 2026

Disclaimer

The information, ratings, and recommendations provided on Dermatocare — including ingredient safety scoring, suitability tags, and dermatologist insights — are for educational purposes only and do not constitute medical diagnosis, treatment, or a doctor-patient relationship. Product assessments are based on publicly available ingredient lists and scientific literature; formulations may change without notice, and Dermatocare does not assume liability for inaccuracies, adverse reactions, or product misuse.

Many companies do not regularly update or disclose their full formulations online, which can limit verification. Users are strongly advised to check the latest ingredient list on the actual product packaging before making purchase or usage decisions. No brand has sponsored, influenced, or paid for the recommendations in this review.

Individuals with allergies, sensitive skin, eczema, newborn or paediatric skin concerns, pregnancy, breastfeeding considerations, or chronic medical conditions should seek personalised medical advice before using any product. Patch testing is strongly advised for all age groups. Dermatocare may earn a commission from affiliate links, but this does not influence our safety or efficacy ratings. All trademarks belong to their respective owners.

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