La Roche-Posay Mela B3 Anti-Dark Spot Serum: Dermatocare review
La Roche-Posay Mela B3 Anti-Dark Spot Serum, formulated with Niacinamide and 2-Mercaptonicotinoyl Glycine, is aligned to Oily, Combination/Normal skin, Non-sensitive skin, with skin concern of Melasma/PIH/Tanning.
Overview
Skin type Oily, Combination/Normal
Skin concern Melasma/PIH/Tanning
Key Ingredients Niacinamide, 2-Mercaptonicotinoyl Glycine
Specs Premium, Not Fragrance Free, Has silicone
Life stage
Formula highlight
- Skin-lightening ingredient: 2-Mercaptonicotinoyl Glycine (Conc. Not found)
- Niacinamide: Conc. Not found
- Anti-aging ingredients: Retinyl Palmitate, Carnosine
- Soothing ingredient: Dipotassium Glycyrrhizate
- Hydrating ingredients: Glycerin, Propylene Glycol, Sodium Hyaluronate, Caprylic/Capric Triglyceride
Keep in mind
- Niacinamide and 2-Mercaptonicotinoyl Glycine percentages not disclosed
People also ask
This product complies with all applicable cosmetic safety regulations. Evaluations provided are based on Dermatocare's independent database criteria, which apply stricter benchmarks than standard regulatory guidelines.
Sensitive skin Cautious use: Contains ingredients flagged in our database as common contact sensitizers. Performing a 24-hour patch test is recommended prior to use.
Pregnancy: Cautious Use - Contains ingredients which is flagged on our Pregnancy Ingredient Database for concentration limits. Can be used for short term/intermittent use, as spot treatment, or in rinse off formula. When in doubt consult your physician.
Teens Caution: Compliant with general cosmetic safety standards, but contains ingredients that may be unnecessary or unsuitable for teen skin (such as potent actives, old chemical filters, ingredients under review). A simpler, minimalist formula may be a better fit. Refer to our Teen Skincare Guide for full details.
No. It does not contain any ingredients currently flagged under Dermatocare's internal evaluation criteria. Refer to our Ingredients Under Review Guide for full database benchmarks.
No. It does not contain ingredients currently flagged for environmental persistence, bioaccumulation, or aquatic toxicity under Dermatocare's database criteria. Refer to our Environmental Screening Guide for full evaluation benchmarks.
Ingredient list
AQUA / WATER / EAU • DIMETHICONE • NIACINAMIDE • GLYCERIN • PROPYLENE GLYCOL • POLYSILICONE-11 • SILICA • BIS-PEG/PPG-16/16 PEG/PPG-16/16 DIMETHICONE • CYSTOSEIRA TAMARISCIFOLIA EXTRACT • 2-MERCAPTONICOTINOYL GLYCINE • PEG-20 METHYL GLUCOSE SESQUISTEARATE • SODIUM HYALURONATE • SODIUM HYDROXIDE • SODIUM THIOSULFATE • CARNOSINE • POLOXAMER 338 • AMMONIUM POLYACRYLOYLDIMETHYL TAURATE • DIPOTASSIUM GLYCYRRHIZATE • CAPRYLIC/CAPRIC TRIGLYCERIDE • CAPRYLOYL SALICYLIC ACID • CAPRYLYL GLYCOL • CITRIC ACID.
Source: https://www.laroche-posay.sg/mela-b3/mela-b3-serum
Date: 15 September 2026
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Disclaimer
The information, ratings, and recommendations provided on Dermatocare — including ingredient safety scoring, suitability tags, and dermatologist insights — are for educational purposes only and do not constitute medical diagnosis, treatment, or a doctor-patient relationship. Product assessments are based on publicly available ingredient lists and scientific literature; formulations may change without notice, and Dermatocare does not assume liability for inaccuracies, adverse reactions, or product misuse.
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